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Stanley Druckenmiller Is Up 18% YTD — Here’s What He’s Holding

Health Care, Coupang, and a whole lot of alpha. We dug into his portfolio and backtested 7 years of his top picks.

TL;DR: TODAY’S EDITION
  • Stanley Druckenmiller’s portfolio is up +18% YTD — crushing the S&P’s +3%

  • His top positions are high-conviction but surgical: top 3 = 30%+ of the portfolio

  • We backtested a strategy that simply copied his top 10 stocks: it would’ve 2x to 3x the S&P over the past 3–7 years

  • His 2025 plays? Biotech, Asia, and high-conviction tech — with a healthy dose of contrarian timing

STANLEY DRUCKENMILLER

Who is Stanley Druckenmiller (and why should you care)?

Stan Druckenmiller isn’t just some guy with a Bloomberg terminal.

He helped Soros “break the Bank of England” in 1992, then ran Duquesne Capital for decades without posting a single down year. Today, he’s managing billions through his Duquesne Family Office — and it still reads like an elite hedge fund.

The difference? He doesn’t have to answer to LPs anymore. Just conviction and results.

🔍 So, What’s He Holding Right Now?

Let’s break down the Top 10 holdings from his Q1 2025 13F:

🧬 Natera (NTRA) – 15.7% of portfolio

A dominant player in genetic testing, especially non-invasive prenatal screening. While Druckenmiller trimmed his stake slightly, it remains his #1 position — signaling strong long-term conviction in biotech’s diagnostics edge.

💊 Teva Pharmaceuticals (TEVA) – 7.5%

He boosted his stake by 65% this quarter. Teva’s comeback story (with debt under control and generics still vital) could be why he’s leaning in now.

🛒 Coupang (CPNG) – 6.7%

Korea’s Amazon. Logistics-first, fast-growth, and now turning profitable. He’s held this since 2021 and added again — showing continued belief in Asia’s ecommerce leaders.

🏗️ Woodward (WWD) – 6.5%

Industrial tech that powers energy and aerospace systems. A quieter bet, but strategic. He trimmed a bit this quarter, but the position is still heavy.

🚬 Philip Morris (PM) – 5.7%

Old-school dividend meets new-world nicotine. He reduced here too — but still holds it big. Might be a value + income hybrid he can trim as growth plays take over.

⚡ Coherent (COHR) – 4.7%

A play on industrial lasers and photonics. Highly cyclical, but big upside when markets recover. The reduction this quarter might just be tactical.

📦 MercadoLibre (MELI) – 3.4%

Latin America’s ecommerce beast. He initiated the position in Q2 2024 and has held steady — likely a bet on rising digital penetration in underbanked markets.

🧪 Insmed (INSM) – 3.4%

Massive +131% increase this quarter. Biotech with a promising treatment for rare lung diseases. One of his boldest moves lately.

🇹🇼 Taiwan Semiconductor (TSM) – 3.2%

The chipmaker that powers the world. Druckenmiller added nearly 5x more shares, showing confidence in AI-driven infrastructure.

🖊️ DocuSign (DOCU) – 2.9%

Brand-new addition. Still a dominant player in digital agreements, possibly undervalued after tech’s recent correction. Stan sees a bounce coming?

📈 What If You’d Copied Him?

We backtested a simple strategy:

👉 Every quarter, replicate his top 10 holdings based on the 13F.

Here’s what would’ve happened:

Timeframe

Druckenmiller

S&P 500 TR

3Y

233,71%

66,55%

5Y

213,8%

109,6%

7Y

307,2%

148,8%

2023–2025 was especially wild:

  • 2023: +43.6%

  • 2024: +72.2%

  • 2025 YTD: +18.1%

So yes — even if you only followed his published filings, you’d still outperform massively.

💡 Why It Works

Druckenmiller isn’t managing a sleepy mutual fund. His strategy:

  • Concentrated bets (Top 3 = 30%+ of portfolio)

  • Biotech & Asia focus = alpha from less crowded trades

  • Bold additions (TSM +457%, Insmed +131%)

  • Tactical cuts — he’s not precious, just effective

It’s part macro wizardry, part stock sniper.

📌 The Takeaway

Stanley Druckenmiller still has it. He doesn’t play the whole market — he picks his shots. And right now, he’s leaning into biotech, international ecommerce, and the infrastructure behind AI.

And if you’d followed along? You’d be way ahead of the average investor.

Want to Go Beyond Druckenmiller?

With Smart Money Premium, you don’t have to guess which investors to follow — we’ve already done the work for you.

  • Access to the Top 20 performing investors on 3-, 5-, and 7-year horizons

  • Their current portfolios, updated quarterly

👉 Upgrade now and start replicating smart money today

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